Huntingtin Exists as Multiple Splice Forms in Human Brain
نویسندگان
چکیده
منابع مشابه
Huntingtin Exists as Multiple Splice Forms in Human Brain.
BACKGROUND A CAG repeat expansion in HTT has been known to cause Huntington's disease for over 20 years. The genomic sequence of the 67 exon HTT is clear but few reports have detailed alternative splicing or alternative transcripts. Most eukaryotic genes with multiple exons show alternative splicing that increases the diversity of the transcriptome and proteome: it would be surprising if a gene...
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ژورنال
عنوان ژورنال: Journal of Huntington's Disease
سال: 2015
ISSN: 1879-6397,1879-6400
DOI: 10.3233/jhd-150151